Im 63 and my bones have now fully recovered from severe osteopenia that was found when I was in my late 40s. And you have to take this in divided doses of 15 mg / 3 times a day as MK-4 is cleared by almost everyone within 4-6 hours. PMID: 20232111. 6. In addition to its antiresorptive activity, strontium was found to have anabolic activity in bone and thus may have significant beneficial effects on bone balance in normal and osteopenic animals. Be well, No cheese, butter, only almond milk and do take yogurt. Strontium is what is responsible for the bone-building effects. Is their anyway to keep the bones healthy, as the doctors have said it is uncurable. A CDSA is not as sophisticated as the OAT but it may be sufficient and it is more likely to be covered by insurance than the OAT. I agree with your assumptions on thyroid and iodinegreat article by the way, I hope others reading these posts will check it outI felt the same way, but I wanted to ask you because I could see that you had already done an extensive amount of research and willing to answer peoples questions/concerns. Great! Hopefully, you can share what you learn and help others in your country as well. And I make sure my husband, who does not have bone density problems, but does have knee joint problems, takes both (he also takes just one capsule of Strontium Boost at night), so he can continue to play basketball. PMID: 25293384 PMCID: PMC4187454. Heres a link to my talk on TBS: https://blog.algaecal.com/how-to-analyze-your-dexa-results-for-bone-quality/ The really good news is that your DXA images can be used to calculate your TBS, so please request that this be done for you when you go in for your next DXA. Strontium ranelate was used in these trials. Meunier, P. J., Slosman, D. O., Delmas, P. D., Sebert, J. L., Brandi, M. L., pam. Who wrote this article? But in taking them separately, does strontium replace calcium in the bones? HRT involves the use of extremely potent estrogens not produced by human women and has numerous adverse effects, including increasing breast cancer risk. I am still, however, in the osteopenia range (but at 85%-89% of normal). Metabolism 2002;51:906 11. strontium) to bind to Ca3(PO4)2. My question has to do with breast cancer. I just had another DEXA scan and the results are also normal, but less good than 3 years ago. Hope this answers your question, Lara, What is a suitable no calcium snack to have with the Strontium Citrate? Obviously, what you are currently doing is not meeting YOUR needs. After SR treatment, there were no significant changes in crystal characteristics. Epub 2005 Sep 29.PMID: 16195514 Thanks so much for looking into all that. https://www.ncbi.nlm.nih.gov/pubmed/22172139. I did not know that; I did take the strontium citrate shortly after eating my breakfast cereal with almond milk, which was fortified with calcium. Thus, I am unable to read the paper in which 170 mg of strontium is said to be more effective, so I do not know what was done and cannot give you more helpful feedback on this. I mentioned this earlier, what are your thoughts on the following statement given in Lis thesis paper (cited above): Interestingly, according to one study, 170 mg of strontium per day was more effective than 680 mg per day for reducing fracture risk (Meunier et al., 2002), which raises the possibility that even lower doses might be as effective as, or more effective than, the dosages that have been studied.. My results have TOTALLY convinced me. Monica. At first I thought it was a one time fluke, but it is happening every night. This is the only change I made to what I had been doing. I have been taking Pure Encapsulations Strontium as per doctors suggestion, but have run out of it. Hope this helps and feel free to let us know if you have any other questions! I agree with you that long-term use of strontium citrate at the full dosage may not be optimal, and why risk it? The other night I contacted the manufacturer of my strontium and inquired as to if the supplement was better absorbed on an empty stomach or with food. three meals of the day, equally effective. This is because food and some drinks can affect the way these medicines work. What is your digestion like, normally? Strontium both lowers osteoclast production and activity and increases osteoblast production and activity. It is overwhelming me to find the right combination of products that will give me the amount of vitamins and minerals recommended to maintain my health, as well as improve my bone density and bone health. Neither were there changes of the cohesion properties of the mineral crystals, which exhibited properties of young bone (i.e., low intracrystal distances). So, they were looking at short term (in comparison to the rest of a postmenopausal womans life span) outcomes. Classic symptoms include widespread rash, fever, and involvement of one or more internal organs. Remember, however, that you are most likely getting calcium from your diet, too this counts! We lose strontium much more rapidly than calcium: three times as much strontium is lost in urine compared to calcium. What is the answer to Goutermans question? The long list of adverse side-effects attributed to strontium ranging from commonly seen adverse effects like nausea and skin irritation to possibly deadly effects like venous thromboembolism and serious autoimmune reactions, such as DRESS are caused by ranelic acid (the ranelate portion of strontium ranelate). PMID: 841579. I am not being paid to respond to questions here on this blog. In other words, whether your bone density increases or not, strontium reduces your risk of breaking a bone! Lis thesis also very nifty I am assuming this was animal research, so results would need to be confirmed in human trials, but his suggestion that calcium will supply nutrition for bone while strontium will display synergistic effects for enhancing bone formation activity and confirmation via the finding that Oral administration of strontium fortified calcium compound significantly increased expression of IGF-I and Runx2 in bone matrix. I appreciate your patience! Just 100 micrograms of MK-7 is effective.) No research indicates that strontium citrate would cause problems for someone with coronary artery disease; however, this is something you should definitely discuss with your doctor before taking strontium or calcium for that matter. Hi Yann, Making collards and beans today! We keep hoping to have a chance to come visit him and see your lovely country. I looked but could find no other study that has replicated these findings or reported similar findings since. I experience this off and on myself, particularly if Ive been doing a lot of gardening, cooking, and housecleaning chores. If you are consuming a Mediterranean-style diet rich in organically grown vegetables (esp leafy greens, whole grains, nuts [eg Brazil nuts are an excellent source of selenium so good that you dont want to consume more than 2 Brazil nuts a day]), then this combined with AlgaeCal Plus will be providing you with a good supply of trace minerals. I searched the literature again for equivalent doses of 170 mg elemental strontium, in every case the higher dose was shown to be more efficacious. Uusi-Rasi K, Kannus P, Karinkanta S, et al. Epub 2012 Apr 23. Hope this helps, Lara, One additional question (I just finished posting my prior questions to you.) The reason 4 hours is recommended is that even if your digestion is slower than normal, you will have absorbed any calcium that was present in your meal or supplements by then. Everyone is different, so high end of normal may be normal for your body. Dialysis is a way of carrying out this process. ), egg products (e.g., Egg beaters, powdered eggs), seafood, and candy (including chocolate). These findings could reflect dose-dependent stimulation of bone formation and are of potential value for the use of SR in the treatment of osteoporosis. This was caused by taking diuretics for 17 yrs because I have Menieres Disease. Because strontium is a highly reactive element, it is never found in a pure form in nature. Epub 2010 Sep 26. Hello! https://www.arthritis.org/about-arthritis/types/calcium-pyrophosphate-deposition-disease-cppd/ A few years ago now, I also started to experience pain in my thumb joints (and sometimes other fingers as well), which would clear out after a few days. I take a few protein shakes to get the lactoferrin, eat mostly vegetarian (loved your navy bean receipe), try to keep urine in alkaline range. A member of the American Medical Writers Association for more than 25 years, Lara publishes and reviews articles covering breaking research on bone health in Integrative Medicine: A Clinicians Journal. 2015 Jan;24(156):15. AlgaeCal Plus provides the key nutrients our bones must have to maintain themselves, regardless of our age, and in amounts shown in the research to be sufficient for most people. So many thanks, Dave and Susan. I have a question re. J Bone Miner Res 2000;15:1526-36.) But like I said if you think you are reacting to something stop using it. PMID: 22614439, Hope this helps answer your really great questions, Lara. In your bones as well as in your digestive tract, strontium and calcium compete for absorption, and calcium wins every time. BMD is being used as a marker of estrogen exposure because estrogen plays numerous roles in the maintenance of healthy bones. 28, no. Interesting what you are saying about gluten. Especially thanks for the links to research. If you dont have a copy, please check it out from your library if you dont wish to buy it. Also, sometimes crystals can form and deposit in a joint a thumb joint version of gout. Lara, Thank you seems so inadequate. We are each UNIQUE. PMID: 23877652 Some have said that strontium replaces calcium in the bones. Heres a link to a blog I wrote discussing how and why soy foods are helpful https://blog.algaecal.com/latest-research-shows-soy-foods-help-prevent-bone-loss/. How much vitamin D3 (I hope she takes D3 as it is significantly more effective for us than D2) is she taking? YOUR best solution is highly likely to be around 180 mcg of K2 as MK-7. In our clinical research, strontium citrate showed no negative side effects, including no evidence was found in cardiovascular risk. Monitoring bone strontium levels of an osteoporotic subject due to self-administration of strontium citrate with a novel diagnostic tool, in vivo XRF: a case study. doi: 10.1136/bmjopen-2014-005787. The other study cited (Korpelainen et al.) One important consideration regarding AlgaeCal is that it is supplying calcium within the naturally absorbed matrix of all the other trace minerals the sea algae used to create its bony structure if you look at Appendix B in which I summarized all the vitamins and minerals healthy bones require, you will see that MANY trace minerals play important roles in our bones. Dont worry about strontium taking the place of calcium in your bones. Unfortunately, we arent familiar with the safety of canned sardines for dogs. I did notice something interesting though; the D.V. I sent the following reply to one of them to share there: I found the discussion and have been looking and looking and looking for any research showing strontium citrate is toxic. The AM packet contains 1g of strontium citrate. re-absorb calcium passing through the kidneys in the bloodstream instead of losing it in urine In all three treatment groups, study participants with above average compliance had significantly greater increases in BMD compared to the losses seen in the two expected-change reference groups. (The creatinine clearance rate is also called the glomerular filtration rate because tiny capillaries in the basic structural and functional unit of the kidney, the nephron, are called glomerular capillaries.). Glad you enjoyed the information, Kalpana! So, my first question for you is, Are you taking your AlgaeCal Plus & Strontium Boost on an empty stomach? Just be sure to have wild caught rather than farm-raised salmon. Re the inflammation (which as you know promotes activation of osteoclasts, so we really need to get that down! I took the strontium citrate via a supplement through Orth Molecular called 0ro Bono. Each session included a 15-min warm-up period. Hi Sheila, Perhaps one of our readers will have insights to share with you! Super Power Bars, Vegan Hemp Butter Protein Bars, Salted Chocolate and Pistachio Energy Bars, or these Raw Sprouted Buckwheat Bars. Sorry that I have not been able to find it on PubMed. What is the measurement being used here? When the feeling of empty stomach is caused by genuine hunger, eating food immediately mitigates the sensation. Prior to using AlgaeCal, I had been rebuilding bone, but SLOWLY. Thank you Lara for that thorough response! Here are a couple of the most recent: Angle SR, Sena K, Sumner DR, Virdi AS. This is what your body is telling you! Yes, my inflammation is under control. I recently found this research study, https://eje.bioscientifica.com/view/journals/eje/165/3/469.xml. Thus, if we take both the supplements together or at the same time, the two will compete for absorption by the body. Signaling through this family of receptors promotes cell proliferation and opposes apoptosis (cell suicide), so too much signaling can increase risk of uncontrolled cell growth, i.e., breast cancer. https://pubmed.ncbi.nlm.nih.gov/25293384/ Did a meta-analysis of S. ranelate and found risks of serious ADRs were similar to benefits. Most of us eat the same foods over and over and do not vary what we eat all that much. I take Strontium Bone Maker every day along with my New Chapter Bone Strength Take Care Calcium supplement. Along with bone-building elements calcium and magnesium, strontium is a member of the elements in Group 2 on The Periodic Table meaning it shares some similar chemical properties. I eat the calcium-dense foods (e.g., yogurt, goat cheese, cottage cheese, soymilk enriched with calcium, tofu, spinach) at breakfast and dinner. I suggest you take a careful look at the labels on the housecleaning and body care products you are using and eliminate any that may be suspect for 4-5 days. I skipped the strontium for 2 nights and I felt like my normal self. For much more on these issues, please listen to my #AskLara on the AlgaeCal Community discussing the differences between HRT and BHRT, also 2 other #AskLara discussing testing that should be done when using BHRT (NO ONE should use HRT!). Thanks. https://www.ncbi.nlm.nih.gov/pubmed/?term=15336592 How does it compare to the AlgaeCal that you recommend? Even at the highest dose of 255 mg Sr21/kg per day, the apatite crystals in the treated animals were intermediates between a physiologic calcium hydroxyapatite and an apatite where one calcium atom out of ten was substituted by a strontium atom. Final ThoughtsWhy Take AHCC On An Empty Stomach? Hope this helps, Lara, Hi Lara, As you know, shortly after maximal bone mass has been accrued (early to mid-30s), women start losing 0.5-1% of their BMD annually, a loss that accelerates to 2% or more during menopause and continues for as many as 10 years afterwards. Re strontium yes, the ratio you want is approximately twice as much calcium as strontium. So delighted you have been helped by the information in Your Bones! Ideally an hour before, or three hours after eating. The only really good food source of vitamin A is liver, which few of us consume regularly any more (and if you do eat it, PLEASE be sure to only consume organic liver!) I have read your book,Your Bones and not really found a specific answer to this question . J Eur Acad Dermatol Venereol. You need both trace minerals to produce and utilize thyroid hormones. Let me know about the algae cal. Re lactoferrin, it looks quite promising. Thanks, delighted you have found the blogs and Your Bones helpful. Strontium increases the production of osteocalcin Incorporation and distribution of strontium in bone. AlageCal is harvested sustainably as evidenced by IBD and IBAMA / Aquamin is not sustainable as evidenced by their move from Ireland to Iceland for harvesting (2006 JBMR 21(9) 1417-24, Its also vitally important to recognize that, Strontium Boost: 2 capsules right before bed (on an empty stomach), Activate vitamin D (vitamin D is converted into its active, hormonal form in the kidneys which is the form in which vitamin D helps us absorb calcium from the digestive tract), Re-absorb calcium passing through the kidneys in the bloodstream instead of losing it in urine. Im sorry to hear about sisters! As always, grateful to you! Here in the US, Your Bones is available in our public libraries. AlgaeCal Plus provides 720 mg of calcium per day (4 capsules 2 AM and 2 PM) and your diet should be giving you the remaining 380 mg of calcium you need to reach a daily intake of 1,200 mg/day. The primary efficacy endpoint was lumbar bone mineral density (BMD), assessed by dual-energy x-ray absorptiometry. I have been taking Strontium citrate since Aug. 30. and it seems I read somewhere that the Strontium exaggerates the results. Strange. It effectively prevents and repairs osteoporosis without the side effects of bisphosphonates. I hope this will fully clear up your confusion, and now that AlgaeCal is aware of the potential for misunderstanding, steps can be taken to make the label on Strontium Boost easier to understand correctly. I take 3 grams of Sodium chloride each day. It is NOT just calcium, but calcium within the matrix of all the trace minerals required by the sea algae to build its bony structure. What do you make of this 2012 study linking strontium to increased incidence of breast cancer? I have your excellent book so I will not ask you to repeat anything from there. Hi Debra, Both the supervised and home exercise programs were updated every 2 weeks to ensure progression and versatility. I also e-mailed Meunier and asked if his cited study (or any he knew of) suggested 170 mg to be more effective than 680 mgas the above people are citing him as demonstrating that. Also (I guess this is a 3rd question) how long do you recommend that someone should stay on these two vitamins (i.e. Useful information. Ive seen this mentioned in comments on several websites. Three women in the exercise group experienced musculoskeletal problems that required minor modifications in their training regimen. It is best to take strontium supplements and calcium at different times of day to get the most benefit. The doses ranged from 100 to 750 mg/kg per day of strontium ranelate, corresponding to 34255 mg/kg per day of Sr21. What amount would you suggest? My understanding is that Supplement Facts are required to list the amount of the element (in this case, strontium). 2010 Jun;23(3):425-30. Re their recommendation of impact exercise for the participants in this study, I believe it was reasonable and helpful here are the reasons why. RESULTS: No correlation (r(2) = 0.29) was found in oral drug bioavailability between rat and human, while a correlation (r(2) = 0.8) was observed for drug intestinal permeability with both carrier-mediated absorption and passive diffusion mechanisms between human and rat small intestine. -2.4 rt. Adults 19-70 years: 15 micrograms (600 IU) Strontium is almost twice as large as calcium, and its larger size impacts DEXA readings. If you tolerate 1 capsule, after several days of taking just 1, take 2, and see how you do. 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